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REBASE is a dynamic, curated database of restriction enzymes and related proteins that should be used as a guide to the ever-changing landscape of restriction enzymes and DNA methyltransferases.

REBASE is an open database provided to benefit the scientific community. Adaptation or distribution of information from REBASE should also remain open and accessible to the public.

If you include or otherwise utilize REBASE information in or for your work, please cite the latest review: PubMed 36318248

Roberts, R.J., Vincze, T., Posfai, J., Macelis, D.
REBASE: a database for DNA restriction and modification: enzymes, genes and genomes.
Nucleic Acids Res. 51: D629-D630 (2023).
doi: 10.1093/nar/gkac975


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In Memory of Donald G. Comb, founder of NEB

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