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Glucosylglycerate synthase

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Glucosylglycerate synthase
Identifiers
EC no.2.4.1.268
Databases
BRENDAenzyme data
ExPASyNiceZyme view
KEGGenzyme entry
MetaCycmetabolic pathway
Rheareactions
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
PubMedarticles
NCBIproteins

Glucosylglycerate synthase (EC 2.4.1.268, Ggs (gene)) is an enzyme with systematic name ADP-glucose:D-glycerate 2-alpha-D-glucosyltransferase.[1] It catalyses the following chemical reaction

The enzyme characterised from Persephonella marina transfers a glucosyl group from adenosine diphosphate glucose to D-glyceric acid, giving 2-O-(α-D-glucopyranosyl)-D-glyceric acid (glucosylglycerate), with adenosine diphosphate (ADP) as a byproduct.[2] It has also been found in Petrotoga mobilis. In both these thermophilic organisms, the product protects againt osmotic stress.[3]

References

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  1. ↑ Enzyme 2.4.1.268 at KEGG Pathway Database.
  2. ↑ Fernandes C, Empadinhas N, da Costa MS (June 2007). "Single-step pathway for synthesis of glucosylglycerate in Persephonella marina". Journal of Bacteriology. 189 (11): 4014–9. doi:10.1128/JB.00075-07. PMC 1913396. PMID 17369297.
  3. ↑ Fernandes C, Mendes V, Costa J, Empadinhas N, Jorge C, Lamosa P, Santos H, da Costa MS (March 2010). "Two alternative pathways for the synthesis of the rare compatible solute mannosylglucosylglycerate in Petrotoga mobilis". Journal of Bacteriology. 192 (6): 1624–33. doi:10.1128/JB.01424-09. PMC 2832527. PMID 20061481.
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