Mannose-1-phosphate guanylyltransferase (GDP)
| Mannose-1-phosphate guanylyltransferase (GDP) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.7.7.22 | ||||||||
| CAS no. | 9026-31-7 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Mannose-1-phosphate guanylyltransferase (GDP) (EC 2.7.7.22) is an enzyme that catalyzes the reversible chemical reaction:
The enzyme characterised from yeast combines guanosine diphosphate and mannose 1-phosphate to give guanosine diphosphate mannose, with pyrophosphate (PPi) as a byproduct.[1]
Nomenclature
[edit]This enzyme is a transferase, specifically one transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is GDP:alpha-D-mannose-1-phosphate guanylyltransferase. Common names in use include:
- GDP mannose phosphorylase
- Mannose 1-phosphate (guanosine diphosphate) guanylyltransferase
- GDP mannose phosphorylase
- GDP-mannose 1-phosphate guanylyltransferase
- Guanosine diphosphate-mannose 1-phosphate guanylyltransferase
- Guanosine diphosphomannose phosphorylase
- Mannose 1-phosphate guanylyltransferase
- GDP:D-mannose-1-phosphate guanylyltransferase[2]
References
[edit]
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