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Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2
2019 · Evan Bolyen, Jai Ram Rideout, et al. · Nature Biotechnology · 23,684
Pembrolizumab versus Chemotherapy for PD-L1–Positive Non–Small-Cell Lung Cancer
2016 · Martin Reck, Delvys Rodríguez-Abreu, et al. · New England Journal of Medicine · 10,075
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PD-1 Blockade in Tumors with Mismatch-Repair Deficiency
2015 · Dung T. Le, Jennifer N. Uram, et al. · New England Journal of Medicine · 9,353
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Effects of Losartan on Renal and Cardiovascular Outcomes in Patients with Type 2 Diabetes and Nephropathy
2001 · Barry M. Brenner, Mark E. Cooper, et al. · New England Journal of Medicine · 7,494
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Caspases: Enemies Within
1998 · Nancy A. Thornberry, Yuri Lazebnik · Science · 6,889
Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade
2017 · Dung T. Le, Jennifer N. Durham, et al. · Science · 6,625
Pembrolizumab plus Chemotherapy in Metastatic Non–Small-Cell Lung Cancer
2018 · Leena Gandhi, Delvys Rodríguez-Abreu, et al. · New England Journal of Medicine · 6,601
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PD-1 blockade induces responses by inhibiting adaptive immune resistance
2014 · Paul C. Tumeh, Christina L. Harview, et al. · Nature · 6,600
Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): a randomised controlled trial
2015 · Roy S Herbst, Paul Baas, et al. · The Lancet · 6,446
Pembrolizumab for the Treatment of Non–Small-Cell Lung Cancer
2015 · Edward B. Garon, Naiyer A. Rizvi, et al. · New England Journal of Medicine · 6,190
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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
2016 · Daniel J Klionsky, Kotb Abdelmohsen, et al. · Autophagy · 5,890
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Pembrolizumab versus Ipilimumab in Advanced Melanoma
2015 · Caroline Robert, Jacob Schachter, et al. · New England Journal of Medicine · 5,881
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Role of AMP-activated protein kinase in mechanism of metformin action
2001 · Gaochao Zhou, Robert Myers, et al. · Journal of Clinical Investigation · 5,647
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Strategies for the Assessment of Matrix Effect in Quantitative Bioanalytical Methods Based on HPLC−MS/MS
2003 · B. K. Matuszewski, M. L. Constanzer, et al. · Analytical Chemistry · 5,354
Merck molecular force field. I. Basis, form, scope, parameterization, and performance of MMFF94
1996 · Thomas A. Halgren · Journal of Computational Chemistry · 5,327
Primary Prevention of Acute Coronary Events With Lovastatin in Men and Women With Average Cholesterol Levels
1998 · John R. Downs, Michael Clearfield, et al. · JAMA · 5,236
Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs
2005 · Lee P. Lim, Nelson C. Lau, et al. · Nature · 4,756
Gait Speed and Survival in Older Adults
2011 · Stephanie Studenski · JAMA · 4,552
Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes
2015 · Christopher P. Cannon, Michael A. Blazing, et al. · New England Journal of Medicine · 4,488
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FinnGen provides genetic insights from a well-phenotyped isolated population
2023 · Mitja I. Kurki, Juha Karjalainen, et al. · Nature · 4,226
Can the pharmaceutical industry reduce attrition rates?
2004 · Ismail Kola, John Landis · Nature Reviews Drug Discovery · 4,167
Comparison of Upper Gastrointestinal Toxicity of Rofecoxib and Naproxen in Patients with Rheumatoid Arthritis
2000 · Claire Bombardier, Loren Laine, et al. · New England Journal of Medicine · 4,017
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Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
1995 · Donald W. Nicholson, Ambereen Ali, et al. · Nature · 3,978
Functional Characterization of the S. cerevisiae Genome by Gene Deletion and Parallel Analysis
1999 · Elizabeth A. Winzeler, Daniel D. Shoemaker, et al. · Science · 3,952
Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures
1996 · Dennis M Black, Steven R Cummings, et al. · The Lancet · 3,844
Works count: 41,990
Works count with child institutions: 48,810
Citation count: 9,371,000
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