Umuti utari umuti urwanya ububyimbirwe
Inyandikorugero:Infobox drug classImiti igabanya ububabare idakoresha steroide ( NSAIDs ) ni ubwoko bw'imiti ikoreshwa cyane cyane mu kuvura ububabare, umuriro, no kubyimba.[1][2] Aspirine ishobora kandi gukoreshwa mu gukumira indwara z'umutima cyangwa indwara zo mu bwonko . Bishobora gufatwa mu kanwa, mu guterwa inshinge, mu gusigwa ku ruhu, cyangwa mu buryo bwo gukamura.[2] Bishobora gukoreshwa hamwe na parasetamol (acetaminophen).[1] Ku bantu bafite ibyago byo kugira ibibazo byo mu gifu, bashobora gufatwa hamwe n'umuti ugabanya ubukana bwa pompe ya proton.[1]
Ingaruka mbi zishobora kuba zirimo ibisebe byo mu gifu, indwara z'umutima, umuvuduko ukabije w'amaraso, n'indwara z'impyiko.[2][3][4] Izindi ngaruka mbi zishobora kuba zirimo indwara ya asima n'uduheri . Ntibikwiye gufatwa mu mezi 3 ya nyuma yo gutwita.[5] Hari ubwoko bubiri bw'ibidatoranywa n'ibidatoranywa bya COX-2.[2] Nubwo imiti itoranya COX-2 ishobora kugira ibyago bike byo kubabara mu gifu, ifite ibyago byinshi byo kurwara indwara z'umutima.[1] Zikora mu kubuza imikorere ya enzymes za cyclooxygenase ( COX-1 cyangwa COX-2 ).[1]
NSAID ya mbere yari aspirine, yatangiye gukoreshwa mu bucuruzi mu 1899, nubwo mbere yakoreshejwe mu buryo bw'igishishwa cy'umukungugu.[6] Ibi byakurikiwe na ibuprofen mu myaka ya 1960 na naproxen mu myaka ya 1970. Inyinshi muri zo ziraboneka nk'imiti isanzwe kandi ntabwo ihenze cyane.[1] Zimwe muri zo zishobora no kugurwa ukoresheje ikarita (OTC).[1] Parasetamol ntabwo ifatwa nk'umuti urwanya indwara zo mu mutwe (NSAID).
Iriburiro
[Hindura | hindura inkomoko]- 1 2 3 4 5 6 7 Hitchings, Andrew; Lonsdale, Dagan; Burrage, Daniel; Baker, Emma (2019). The Top 100 Drugs: Clinical Pharmacology and Practical Prescribing (in Icyongereza) (2nd ed.). Elsevier. p. 168. ISBN 978-0-7020-7442-4. Archived from the original on 2021-05-22. Retrieved 2021-11-09.
- 1 2 3 4 Ghlichloo, I; Gerriets, V (January 2021). "Nonsteroidal Anti-inflammatory Drugs (NSAIDs)". StatPearls. PMID 31613522.
- ↑ Bally M, Dendukuri N, Rich B, Nadeau L, Helin-Salmivaara A, Garbe E, Brophy JM (May 2017). "Risk of acute myocardial infarction with NSAIDs in real world use: bayesian meta-analysis of individual patient data". BMJ. 357: j1909. doi:10.1136/bmj.j1909. PMC 5423546. PMID 28487435.
- ↑ Lanas A, Chan FK (August 2017). "Peptic ulcer disease". Lancet. 390 (10094): 613–624. doi:10.1016/S0140-6736(16)32404-7. PMID 28242110. S2CID 4547048.
- ↑ "List of Common NSAIDs + Uses, Types & Side Effects". Drugs.com (in Icyongereza). Archived from the original on 17 April 2021. Retrieved 27 April 2021. Archived 17 Mata 2021 at the Wayback Machine
- ↑ Ross, Stewart (2020). Who Invented Underpants?: The Weird Trivia of Human Invention, from Fire to Fast Food (and Everything In Between) (in Icyongereza). Simon and Schuster. p. 58. ISBN 978-1-64604-097-1. Archived from the original on 2021-08-28. Retrieved 2021-04-27. Archived 2021-08-28 at the Wayback Machine
