BioMarin Pharmaceutical Inc.

A moving conversation with Zelda La Grange, former private secretary to Nelson Mandela, anchored BioMarin’s recent U.K. Black History Month Town Hall in London. Hosted by the Europe and Canada chapter of our Black Employee Resource Group (BERG), the event explored allyship, community and personal transformation. Drawing on her experience growing up in apartheid-era South Africa, Zelda described questioning inherited beliefs and emphasized that meaningful change requires courage, humility, listening and a willingness to learn. A key takeaway was Ubuntu – “I am because we are” – a philosophy of shared humanity and interconnected wellbeing. It reinforced allyship in practice: listening to different perspectives, challenging assumptions, amplifying voices and taking meaningful action. Black History Month activities also included an interactive Black History treasure hunt around the London office, a Caribbean lunch and support for the Sickle Cell Society. Thanks to all our colleagues who coordinated these opportunities to celebrate culture, learn from history and strengthen community.

For much of his career, Arpit Davé has been fascinated by an idea: Some of the biggest opportunities in biopharma lie not in the science alone, but in how organizations can most effectively learn from the vast amounts of data that science generates. Long before today's excitement around AI, Arpit saw the potential for technology to help researchers uncover new insights, connect information and make better decisions. The challenge was that the ambition often outpaced the tools available to support it. But in recent years, he says, technology has caught up enough to turn potential into reality. "My career journey has really been about cracking this complex problem of using technology and data, and now this powerful tool of AI, to allow companies to fulfill their mission, which is to serve patients,” Arpit says. “There has never been a time like the present for using technology to deliver on the promise of science to improve human health – now it’s on us to seize the moment.” We recently sat down with Arpit, who joined BioMarin earlier this year as Chief Digital Information Officer, to discuss his career journey, what brought him here and how he envisions combining the company’s three decades of scientific expertise with emerging technology to accelerate impact for people with rare genetic conditions. Read more: http://ms.spr.ly/6043avOgz

Throughout Hispanic Heritage Month, BioMarin’s LatinX Employee Resource Group (ERG) brought colleagues together to celebrate culture, community and opportunities for students to explore science. At Novato Unified School District’s Empower Tomorrow event at College of Marin, LatinX members supported hands-on biotechnology activities for eighth-grade students from Sinaloa, San Jose and Hamilton Middle Schools, with BioMarin colleagues Sergio Covarrubias and Augusto Seminario helping students learn about careers in science and engineering. LatinX continued its community engagement with a volunteer event for the Boys & Girls Clubs of Napa Valley, where colleagues assembled STEM kits for local youth and supported the organization’s upcoming STEM Showcase. Thank you to the LatinX ERG and all who helped make this past Hispanic Heritage Month so meaningful.

For Sarita, connection is found in the simplicity of everyday moments: drawing, spending time with her dad and volunteering at a nearby nursing home. The 16-year-old from Colombia brings warmth and thoughtfulness to the people around her in quiet but meaningful ways. Family is at the center of Sarita's world, especially her bond with her father, William. She speaks about him with pride, cherishing the moments they share together and the opportunity to show her appreciation in simple ways. “When he comes home tired from work, I make him a cup of coffee,” she says. “I make it with a little lemon and a little bit of love, and I serve it to him so he can enjoy it.” Sarita lives with #mucopolysaccharidosis (#MPS) type VI, a progressive, rare genetic condition also known as Maroteaux‑Lamy syndrome that leads to the buildup of complex carbohydrates, which can cause complications to multiple organs. The support surrounding Sarita has helped her navigate both the challenges and everyday moments of life with MPS. Her father has been a steady source of encouragement, and she fondly remembers a physician who cared for her when she was younger and helped her better understand what to expect. With that foundation behind her, Sarita has been able to approach life with confidence. Looking ahead, Sarita hopes to work with children, helping them learn and grow while encouraging them to believe in themselves. “I'd like to teach them how to walk, talk, paint and write,” she says. “I'd also like to teach them good manners so they can grow up to be better people.” Sarita dreams of building a happy future with a family of her own, creating the same sense of love and support that has been such an important part of her life. Her story is a reminder of the power of being seen for all that we are, the people we love and the kindness we show others along the way. #FacesOfMPS

Our team is feeling energized and grateful after a great weekend at the American Society for Bone and Mineral Research (ASBMR) Annual Meeting, where we had the chance to connect with leading researchers and clinicians who are driving innovation for people living with skeletal conditions. This collaboration is integral to advancing our shared goal of improving outcomes for those affected by rare genetic conditions. #ASBMR2026

Today we announced new data at the American Society for Bone and Mineral Research (ASBMR) Annual Meeting, highlighting advances in research across multiple skeletal conditions. These results add to a growing body of evidence deepening scientific understanding of skeletal dysplasias and reflect our ongoing commitment to improving outcomes for people living with these conditions. Learn more about the updates we’re sharing at #ASBMR2026: http://ms.spr.ly/6011aUqIT

BioMarin employees joined policymakers, patient advocates, healthcare professionals and members of the rare disease community last week at the European Parliament in Brussels for an expert briefing on newborn screening. The session focused on how to address inequalities in newborn screening across EU member states – some of which screen for as many as 40 rare diseases at birth, while others screen for as few as two. Rachel Finnegan, who leads BioMarin’s Government Affairs work in Europe and Canada, spoke at the briefing, highlighting three main areas where the EU could enact meaningful change, including: 1. Establishing an EU expert advisory committee to help member states keep screening panels up to date as new treatments are approved 2. Recognizing evidence from national screening pilots, so that the same work does not need to be repeated across member states 3. Funding capacity building and the expansion of screening panels We thank MEPs Billy Kelleher and Nicolas Gonzalez Casares for co-hosting this session, as well as EURORDIS-Rare Diseases Europe, EUCOPE – European Confederation of Pharmaceutical Entrepreneurs and the European Parliamentary Research Service for contributing to the meaningful discussion. This was an important dialogue ahead of an upcoming vote on the EU’s Rare Disease Action Plan, which if enacted would be a major step in the direction of greater equity in newborn screening – and for rare diseases more broadly – across the region. We’re committed to working toward a future where newborn babies throughout the EU and beyond are screened for more rare genetic conditions so that families can receive accurate diagnoses and timely connection to care.

We’re thrilled to welcome Cara Bauer (she/her) to BioMarin as our new Chief People Officer. Cara brings more than 25 years of experience as a leader in human resources across the biopharmaceutical and technology industries. She has a track record of building and scaling organizations through periods of rapid growth and change. We look forward to the valuable perspective Cara will bring to the role, and thank Amy Wireman, who is retiring after 14 years at BioMarin. Amy has played a tremendous role in shaping the company and we wish her all the best in her retirement. Read more: http://ms.spr.ly/6042aWnTr

Today we announced new five-year Phase 3 data in adults with late-onset Pompe disease at the Annual Congress of the World Muscle Society. These findings showcase long-term benefits for individuals living with this rare genetic condition, including people who had previously received enzyme replacement therapy and those who had not. Learn more about the data presented here: http://ms.spr.ly/6041alo1d #WMS2026

Archie is happiest when he's on a boccia court or spending time with family. At 25 years old, he lives in the west of England with his parents and younger brother, Isaac, and has built much of his life around the sport he loves. As a boccia coach, competitor and business owner, Archie spends his days helping others discover the game while continuing to pursue his own goals within the sport. “I’m happiest playing boccia and spending time with family,” says Archie. “I’m not a big partier. I prefer nice, quiet meals out.” Archie lives with #mucopolysaccharidosis (MPS) type IVA, also known as Morquio A syndrome, a rare genetic condition that affects the body's skeletal system and can lead to complications affecting multiple organs. Diagnosed at 2 years old, he does not remember life before MPS, but he knows that receiving a diagnosis brought his family something invaluable: answers. “When my parents were told it was MPS, it gave them a roadmap,” Archie says. “Before that, there was so much uncertainty about what life might look like. Getting the diagnosis helped them understand how to cope and what support I might need.” As he grew older, Archie focused his energy on the things that mattered most to him. While MPS has brought challenges, including major hip replacement surgery and increased wheelchair use, he has never let those experiences define him. Instead, he has built a successful coaching business and achieved success in boccia, competing at the National Finals. One lesson Archie wishes more people understood is that a physical disability does not change who someone is. “Yes, I have a physical disability, but that is all it is,” he says. “People do not need to treat me differently from anybody else.” Throughout his journey, Archie has found support not only from his family, particularly his mother, but also from the wider MPS community. Through the MPS Society UK, here for those with rare diseases, he has connected with other people living with MPS, attended conferences and built friendships with peers who understand the realities of living with a rare disease. More recently, he became an ambassador for the organization, helping to shape its future and support others in the community. Looking ahead, Archie hopes to help grow the sport of boccia and create more opportunities for athletes around the world. He dreams of seeing the classification of boccia in which he competes – BC5 – gain international recognition, and one day hopes to play at the Paralympic Games. He also hopes his story can help others who are just beginning their MPS journey. “When you have a diagnosis, it helps to have a roadmap,” Archie says. “Sharing my story is about helping other people build that roadmap and demonstrating what’s possible.” #FacesOfMPS