The Journal of Clinical Psychiatry

A nationwide cohort study published in JCP finds that a sibling’s psychiatric history was most informative for postpartum psychosis risk among women with no prior psychiatric diagnosis, suggesting family history may help flag at-risk women who lack established clinical predictors. JCP → https://lnkd.in/dYWrGpep #PostpartumPsychosis #PerinatalPsychiatry #JCP

An article published in JCP reviews 4 cohort studies with 5 to 25 years of follow-up and finds no evidence that electroconvulsive therapy is associated with an increased long-term risk of dementia. JCP → https://lnkd.in/gg-xXAAY #ECT #Psychiatry #JCP

A systematic review and meta-analysis published in JCP suggests lithium prophylaxis may help prevent postpartum mood recurrence in women with bipolar disorder, though the evidence comes from a small, observational literature with no randomized trials. JCP → https://lnkd.in/g4R8Q2z4 #BipolarDisorder #PerinatalPsychiatry #JCP

In the latest installment of JCP’s author webinar series, where authors are invited to share more about their work and its implications, Balwinder Singh, MD, and Raman Baweja, MD, discuss their real-world cohort finding that GLP-1 receptor agonist use was associated with a lower risk of kidney replacement therapy in adults with bipolar disorder and chronic kidney disease, and how to monitor lithium when starting one.  https://lnkd.in/ghZtyMMb #BipolarDisorder #GLP1 #JCP

A consensus panel published in JCP reviewed two recent network meta-analyses of the five FDA-approved adjunctive atypical antipsychotics for MDD and concluded that efficacy and tolerability should be weighed together, with the final choice made through shared decision-making. JCP → https://lnkd.in/gEWpe7T3

A nationwide Taiwan study published in JCP found that after starting a long-acting injectable antipsychotic in bipolar disorder, psychiatric outpatient visits rose and ED visits fell. The findings are associations, and relapse was not measured. JCP → https://lnkd.in/d5wnHvEw #BipolarDisorder #LongActingInjectables #JCP

An ASCP Corner commentary in JCP reviews a preliminary randomized trial in which low-dose buprenorphine after a single ketamine infusion kept suicidal symptoms reduced for at least 31 days, while the placebo group began to relapse at day 10. The authors stress it is untested in the ED. JCP → https://lnkd.in/dcUahpRn #SuicidePrevention #EmergencyPsychiatry #JCP

An exploratory VA study published in JCP suggests monitoring suicide risk may need to continue after a high-risk flag is removed: among veterans who died by suicide, follow-up and suicide-specific assessment declined after flag removal but rose in those who stayed flagged. JCP → https://lnkd.in/gnDwgdFT #SuicidePrevention #VeteranMentalHealth #JCP

When a consensus panel of early adopters published its recommendations on xanomeline-trospium (XT) in JCP, the question was how clinicians were making it work in practice. Nearly two years after approval, the JCP Podcast is circling back. Panel chair Dr. Ilan Melnick joins to share what’s been learned since. Inside: how M1/M4 muscarinic agonism differs from D2 blockade, titration to maintenance doses (and why some patients stall at 100 mg), prophylactic ondansetron and empty-stomach dosing, telling cholinergic from anticholinergic adverse events, cross-titrating from dones, pines, and partial agonists, early use in first-episode psychosis, antipsychotic dose sparing, and two new Psych Congress posters on real-world prescribing and EMERGENT-5 retention. Listen to the full podcast here -----> https://lnkd.in/d2Jgtx3U #Schizophrenia #XanomelineTrospium #Muscarinic #Psychopharmacology #JCPPodcast

What does trauma psychiatry have to do with sleep? On the JCP Podcast, Dr. Steven Berkowitz joins to talk about childhood trauma, prevention, and the open questions around psychedelic research in children and adolescents. Inside: why he doesn't think we can treat our way out of the mental health crisis, why he says trauma psychiatry "is about sleep psychiatry," and what role psychotherapy should play in any future youth psychedelic trial. Also covered: the CFTSI early intervention model, how trauma presents in autistic youth, delayed-onset PTSD in forensic work, and the limits of the DSM. Listen to the full podcast here -----> https://lnkd.in/d3s6Sger