Overview
- A comprehensive overview of the diversity of nucleolar function
- Data presented comes from a wide spectrum of species
- Leading edge studies presented shed new light on nucleolar processes
- Biomedical aspects of nucleolar function are detailed
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About this book
This book contains 14 original review chapters each yielding new, exciting and intriguing data about the emerging understanding of nucleolar structure and function in normal, stressed and diseased cells. The goal of this work is to provide special insight into the nucleolus of the past, present and future, as well its regulation, translocation, and biomedical function. A multitude of topics are introduced and discussed in detail, including nucleologenesis, nucleolar architecture, nucleolar targeting, retention, anchoring, translocation, and the relationship between the nucleolus and cancer. This book also brings together work from several different species, from human to Drosophila to Dictyostelium and other eukaryotic microbes. The final chapter summarizes some of the issues brought up in the various chapters with a view to future research. This book supports the continued emergence of the nucleolus as a dynamic intranuclear region that oversees a vast diversity of events.
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Table of contents (16 chapters)
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Front Matter
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Introduction
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Front Matter
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The Nucleolus and Nucleolar Proteins
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Front Matter
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Nucleolar Protein Translocation
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Front Matter
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Nucleolar Proteins and Disease
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Front Matter
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Editors and Affiliations
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Bibliographic Information
Book Title: Proteins of the Nucleolus
Book Subtitle: Regulation, Translocation, & Biomedical Functions
Editors: Danton H O'Day, Andrew Catalano
DOI: https://doi.org/10.1007/978-94-007-5818-6
Publisher: Springer Dordrecht
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Science+Business Media Dordrecht 2013
Hardcover ISBN: 978-94-007-5817-9Published: 09 March 2013
Softcover ISBN: 978-94-007-9718-5Published: 12 April 2015
eBook ISBN: 978-94-007-5818-6Published: 26 February 2013
Edition Number: 1
Number of Pages: VI, 371
Topics: Protein Science, Cancer Research, Biomedicine general, Biological Microscopy
