Hydroxyacid-oxoacid transhydrogenase
| hydroxyacid-oxoacid transhydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.1.99.24 | ||||||||
| CAS no. | 117698-31-4 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, hydroxyacid-oxoacid transhydrogenase (EC 1.1.99.24) is an enzyme that catalyzes the chemical reaction
-3-hydroxybutyric_acid.svg)
-2-hydroxyglutaric_acid.svg)
The two substrates of this enzyme are (S)-3-hydroxybutyric acid and α-ketoglutaric acid. Its products are acetoacetic acid and (R)-2-hydroxyglutaric acid.[1]
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with other acceptors. The systematic name of this enzyme class is (S)-3-hydroxybutanoate:2-oxoglutarate oxidoreductase. This enzyme is also called transhydrogenase, hydroxy acid-oxo acid.[2]
See also
[edit]References
[edit]- ↑ Enzyme 1.1.99.24 at KEGG Pathway Database.
- ↑ Kaufman EE, Nelson T, Fales HM, Levin DM (1988). "Isolation and characterization of a hydroxyacid-oxoacid transhydrogenase from rat kidney mitochondria". J. Biol. Chem. 263 (32): 16872–9. doi:10.1016/S0021-9258(18)37472-6. PMID 3182820.
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