Azatadin
 | |||
| (IUPAC) ime | |||
|---|---|---|---|
| 11-(1-metilpiperidin-4-iliden)-6,11-dihidro- 5H-benzo[5,6]ciklohepta[1,2-b]piridin | |||
| Klinički podaci | |||
| Robne marke | Optimin | ||
| AHFS/Drugs.com | Mikromedeks, detaljne potrošačke informacije | ||
| Identifikatori | |||
| CAS broj | 3964-81-6 | ||
| ATC kod | R06AX09 | ||
| PubChem[1][2] | 19861 | ||
| DrugBank | DB00719 | ||
| ChemSpider[3] | 18709 | ||
| UNII | 94Z39NID6C  | ||
| KEGG[4] | D07482 | ||
| ChEBI | CHEBI:2946 | ||
| ChEMBL[5] | CHEMBL946 | ||
| Hemijski podaci | |||
| Formula | C20H22N2 | ||
| Mol. masa | 290,402 g/mol | ||
| SMILES | eMolekuli & PubHem | ||
| |||
| Farmakoinformacioni podaci | |||
| Trudnoća | ? | ||
| Pravni status | |||
Azatadin je antihistaminik i antiholinergik.
- ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.
- ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
- ↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846.
- ↑ Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.
- ↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594.
- Zhang D, Hansen E, Deck J, Heinze T, Sutherland J, Cerniglia C (1996). „Fungal biotransformation of the antihistamine azatadine by Cunninghamella elegans.”. Appl Environ Microbiol 62 (9): 3477–9. PMC 168147. PMID 8795241.
- Katelaris C (1990). „Comparative effects of loratadine and azatadine in the treatment of seasonal allergic rhinitis.”. Asian Pac J Allergy Immunol 8 (2): 103–7. PMID 1982614.
- Small P, Barrett D, Biskin N (1990). „Effects of azatadine, terfenadine, and astemizole on allergen-induced nasal provocation.”. Ann Allergy 64 (2 Pt 1): 129–31. PMID 1968324.
